Synergistic Effect of Co‐Culturing Breast Cancer Cells and Fibroblasts in the Formation of Tumoroid Clusters and Design of In Vitro 3D Models for the Testing of Anticancer Agents (Adv. Biology 4/2023)

In Vitro Tumor Model article number 2200141, Joaquim M. Oliveira and co-workers show the development of a silk hydrogel-based 3D in vitro breast cancer model. The model highlights importance matrix stiffness cells fibroblasts interaction for tumor progression, which influence chemotherapeutic drug treatment response. developed will allow deeper understanding tumor-stroma interactions, leading to possibility patient-specific therapies future.